Cardiovascular disease (CVD) is a major cause of death worldwide, estimated at about 2.4 million deaths annually in 1995. Although the global burden of CVD is estimated at USD 6.5 billion in 2016, it is estimated to be reduced by about 50% to 51% of the global burden of disease by 2025. The estimated burden of CVD worldwide at the population level is approximately 13.5 million deaths annually, and is expected to increase by an estimated 16 million deaths by 2050.1
In recent years, a growing number of studies have reported a decrease in the incidence and mortality of CVD, leading to a rise in the prevalence of CVD in various sub-groups including elderly, women, and patients with comorbidities.1
However, the risk of CVD increases with age and may be higher in patients with diabetes mellitus, hypertension, and dyslipidemia.2 In addition, studies have also shown that high-dose statins can be used as long-term treatment in patients with CVD for the prevention of cardiovascular disease (CVD) and prevention of the development of atherosclerosis.3,4
There are several strategies for reducing the risk of CVD, but there are limited data on the efficacy of these strategies. The effectiveness of statins in the prevention of CVD has not yet been established, and the results of the previous clinical trials did not show statistically significant effects on CVD risk.5
A recent meta-analysis of clinical trials showed that there was no significant difference in the rates of CVD incidence among different statin groups (n = 813).5
Although there is a lack of clinical evidence to establish the effect of statins on CVD, a recent meta-analysis suggested that they have a protective effect against CVD in patients with diabetes mellitus, hypertension, and dyslipidemia, with a lower risk of developing CVD and cardiovascular disease.6,7
In the present study, we evaluated the effect of long-term statin therapy with rosuvastatin (Valtrex, Arimidex, or Crestor) on the risk of CVD in patients with diabetes mellitus, hypertension, and dyslipidemia, and their effect on the cardiovascular outcomes. To our knowledge, this is the first meta-analysis to evaluate the effect of long-term statin therapy on the risk of CVD and cardiovascular outcomes in patients with diabetes mellitus, hypertension, and dyslipidemia.
Adult patients with established diabetes mellitus, hypertension, or dyslipidemia, who were treated with at least one of the 3 statin drugs for at least 3 months at the time of enrollment, who had at least one risk factor for CVD (including at least one of the following: obesity, hyperlipidemia, or diabetes mellitus, hypertension, and dyslipidemia, and a history of stroke, myocardial infarction, or coronary revascularization) at the time of enrollment, were included in the present analysis.
The primary outcome was cardiovascular (CV) mortality. This was a retrospective study from the database of the National Health Insurance Research Database (NHI Data Repository), which was updated in October 2016. The analysis was performed using the Kaplan-Meier method. The risk of CVD was measured using the Cockcroft-Gault formula with the lowest available effective rate (ie, less than 15%) for the overall incidence of CVD at least 1 year after the start of statin therapy.
The primary endpoint of the present analysis was the incidence of CV mortality, which was defined as the number of deaths or nonfatal myocardial infarction (MI) events per 1000 person-years (ie, more than 30% of the total number of deaths or nonfatal MI events) in patients treated with at least one statin drug at the time of enrollment. The risk of CVD was defined as the number of deaths or nonfatal MI events per 1000 person-years (ie, more than 30% of the total number of deaths or nonfatal MI events) in patients treated with at least one statin drug at the time of enrollment.2
The secondary outcome was the cardiovascular (CV) mortality, which was defined as the number of nonfatal myocardial infarction (MI) events per 1000 person-years (ie, more than 30% of the total number of deaths or nonfatal MI events) in patients treated with at least one statin drug at the time of enrollment.
CRESTOR 5 TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 5 TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking CRESTOR 5 TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 5 TABLET if you are pregnant or breastfeeding without consulting your doctor.
CRESTOR 5 TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 5 TABLET as a precaution.
The most common side effects of taking CRESTOR 5 TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 5 TABLET.
How should I take CRESTOR 5 TABLET? CRESTOR 5 TABLET should be taken with or without food. Take CRESTOR 5 TABLET at the same time each day as you take medicine to reduce the amount of food causing side effects. The dose and duration of CRESTOR 5 TABLET should be taken exactly as prescribed by your doctor. Swallow CRESTOR 5 TABLET with a full glass of water. Do not take CRESTOR 5 TABLET more than once a day unless your doctor has told you to. Follow your doctor’s instructions until you are gone the longest.The most common side effects of taking CRESTOR 5 TABLET are pain in the joints, changes in mood and frequency of ejaculation, particularly in women who are pregnant. However, some other side effects can beManagement of high cholesterol levels in the blood can result in serious health problems. People with a family history of heart and liver disease should also avoid taking CRESTOR 5 TABLET. They should also avoid using any medication in combination with CRESTOR 5 TABLET such as liraglutide, glipizide or indomethacin. A common side effect of indomethacin is dizziness. common side effects of glipizide include drowsed food, drowsy feeling, confusion, dandruff, fainting, dry skin,"},{"ANSALLEMhanooftominings.comyes
have a read my answer to your question. I am not sure if this is right for you. Take CRESTOR 5 TABLET as advised by your doctor.
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So, when you buy CRESTOR 5 TABLET, you will be buying the medication from a doctor. So, what are the benefits? You will get the drug with the following: 1 tablet per day 2 capsules per day.
The main benefits of taking CRESTOR 5 TABLET at the same time as taking CRESTOR 5-50 mg are are cholesterol levels being reduced, the blood cholesterol levels being reduced, and the use of other healthy lifestyle changes such as regular exercise.
Take CRESTOR 5-50 mg beforerm as it is usually given as a 30-40mg dose. The main benefits of taking CRESTOR 5-50 mg at the same time as taking CRESTOR 5-50 mg atatilde are are can be, 1 tablet per day 2 capsules per day. The capsule can be taken with or without food, but it is better to take it at a fixed time.
Crestor, known generically as rosuvastatin, plays a crucial role in managing various conditions, including heart failure and certain types of cholesterol-related diseases, by inhibiting the enzyme responsible for cholesterol synthesis. This medication functions by reducing the levels of cholesterol in the liver and increasing the levels of a natural substance known as lipase. By doing so, rosuvastatin can slow down or even stop the progression of atherosclerosis, a common sign of heart disease.
Crestor has been recognized for its efficacy in managing cholesterol levels and lowering the risk of heart disease, although research is limited. Rosuvastatin is a member of the class of statins, which work by reducing the amount of cholesterol in the bloodstream. By inhibiting the enzyme responsible for cholesterol synthesis, rosuvastatin helps to reduce the amount of cholesterol in the bloodstream and thereby slow down or stop the progression of atherosclerosis.
The primary mechanism of action of rosuvastatin is its ability to block the enzyme responsible for cholesterol synthesis, known as phosphodiesterase type 5 (PDE5). By blocking this enzyme, rosuvastatin reduces the amount of cholesterol in the bloodstream, thereby reducing the risk of atherosclerosis and improving patient outcomes. By doing so, rosuvastatin can help to maintain healthy blood vessels, reducing the risk of cardiovascular events and improving quality of life.
Crestor is available as an oral tablet or as a topical cream applied directly to the skin to improve symptoms associated with rosuvastatin-induced liver injury. This medication has been shown to be well-tolerated in clinical studies, with few side effects noted. While rosuvastatin is generally well-tolerated, it is important to note that it can cause side effects, which may include dizziness, headache, and nasal congestion. If you experience any severe side effects, such as chest pain or difficulty breathing, seek medical attention immediately.
The effectiveness of rosuvastatin in managing the side effects associated with rosuvastatin use has been well-documented. Studies have shown that rosuvastatin can be highly effective in reducing lipid levels and improving lipid profiles in patients with various lipid levels. However, individual responses and tolerability can vary, and it is crucial to consult with a healthcare provider before starting treatment.
It is important to note that rosuvastatin does not work immediately to alleviate symptoms such as muscle pain, fever, or swelling. Therefore, it is advisable to take the medication as soon as possible to ensure that it does not become life-threatening. Regular monitoring of liver function is crucial to ensure safety and effectiveness.
It is also important to note that while rosuvastatin is an effective medication for managing various heart conditions, it is not suitable for everyone. It is recommended to consult with a healthcare provider before starting any treatment, including rosuvastatin. Regular monitoring and dosage adjustments may help minimize potential side effects.
VIDEOCrestor is a well-known medication used to treat various forms of benign hypertriglyceridemia, including:
Crestor (rosuvastatin) is used to lower cholesterol levels in people who are at risk of developing heart disease and stroke. It helps to reduce the risk of high cholesterol and other cardiovascular complications such as heart attack, stroke, and coronary heart disease. This medication can be used to lower high cholesterol levels in people who are at risk of developing heart disease and stroke.
Crestor is in the United States, Europe, the Middle East, Canada, Japan, Australia, and more. The most common side effects include headache, nausea, diarrhea, and fatigue. Crestor is not FDA-approved to treat high cholesterol, and doctors usually advise people who have cholesterol-related conditions to avoid Crestor.
Common side effects include:
More severe side effects include:
Before taking this medication, tell your doctor or pharmacist if you are allergic to rosuvastatin or any other ingredients in this medication. This drug may make your skin more sensitive to sunlight. Before using this medication, tell your doctor or pharmacist your medical history, especially of:
It is not known whether this drug is safe for people with certain heart conditions. Talk to your doctor before taking this drug if you have any of these serious side effects:
Like all medications, this drug can cause side effects. If side effects are severe or do not go away, talk to your doctor.
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